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Piperine is a pungent compound found in black pepper (Piper nigrum) known for its various health benefits. It has a long history of use in Ayurvedic medicine as a restorative tonic and for enhancing the bioavailability of other foods and herbs in traditional herbal formulas (Prasad et al., 2015). Research has shown that Piperine can increase the bioavailability of turmeric root by 20-fold (Shoba et al., 1998).

The use of piperine extract derived from black pepper fruit dates back to ancient times, with references found in Sanskrit literature from as early as 100 BC. Black pepper was widely used in the Middle Ages to mask the taste of salt-cured meats and was highly valued, even serving as a form of currency. Its importance is evident in historical events, such as when 3000 pounds of black pepper were demanded alongside gold, silver, and silk as ransom to free Rome from the Huns (Prasad et al., 2015).

Piperine has been found to enhance the absorption of nutrients that are typically difficult for the body to metabolize. It may inhibit certain enzymes responsible for the nutrient breakdown and stimulate amino acid transporters in the intestinal lining, allowing for increased nutrient availability over an extended period (Atal et al., 1985; Bhardwaj et al., 2002). Additionally, Piperine may reduce intestinal activity, enabling more active components to enter the bloodstream in higher quantities. Its stimulating effect has been shown to support the release of digestive enzymes by the pancreas, leading to the reduced transit time of food in the gut. These effects contribute to the improved utilization of substances in the body, making black pepper or cayenne a common ingredient in traditional herbal formulas (Prasad et al., 2015).

Piperine has also demonstrated potential benefits for brain health due to its ability to cross the blood-brain barrier and facilitate the transport of other nutrients. It may support healthy levels of beta-endorphins and serotonin, positively influencing mood. Piperine is often regarded as a nourishing brain tonic and has directly affected various nutrients, including CoQ10, vitamin B6, curcumin, amino acids, selenium, and glucose. It can also affect the metabolism of certain enzymes, such as CYPLa1, CYP1b1, CYP1b2, CYP2e1, and CYP34a, as well as several over-the-counter and prescription drugs. It is important to be cautious of Piperine’s ability to increase the bioavailability and potentially enhance the action of these medications (Atal et al., 1985; Bhardwaj et al., 2002; Prasad et al., 2015).

Scientific studies have provided further evidence of Piperine’s benefits. A study published in the Journal of Food and Chemical Toxicology demonstrated that Piperine positively affected mood and cognitive performance at various doses, highlighting its potential as a powerful functional food for the brain (Mittal et al., 2012). Another study published in Planta Medica investigated the combination of Piperine with curcumin to evaluate curcumin’s bioavailability in healthy humans. The results showed that Piperine significantly increased the blood concentration of curcumin and enhanced its bioavailability by 2000% (Shoba et al., 1998).

Incorporating Piperine into your diet, whether as a supplement or through daily food intake, is a great way to add flavor to your meals while maximizing their nutritional benefits. Including spices in your daily routine can provide a powerful boost of nourishment (Prasad et al., 2015).

Some possible traditional uses of Piperine Extract Powder may include:

• May support a healthy pain response

• May support healthy levels of beta-endorphins

• May support healthy serotonin & dopamine levels

• May support healthy adrenals

• May support a healthy gut

• Bio enhancement

• May support the production of pancreatic enzymes

• May support a healthy inflammation response

• Combating the formation of new fat cells

• Combating malabsorption and malnutrition

• May support a healthy histamine response

• May support brain health

• May support the transporting of other nutrients and herbs

This product is 100% natural and minimally processed. Taste, smell, texture, and color may vary from batch to batch.

May lower cholesterol levels

High blood cholesterol is associated with an increased risk of heart disease, which is the leading cause of death worldwide.

Black pepper extract has been studied potential to reduce cholesterol levels.

In one 42-day study fed a high-fat diet and a black pepper extract had decreased blood cholesterol levels, including LDL (bad) cholesterol. The same effects were not seen in the control group.

Additionally, black pepper and piperine are believed to boost the absorption of dietary supplements that have potential cholesterol-lowering effects like turmeric and red yeast rice.

For example, studies have shown that black pepper may increase the absorption of the active component of turmeric — curcumin — by up to 2,000%.

Detoxifies Your Body:

This spice helps you sweat and urinate a lot and by this, you discharge all toxins from your body. Sweating and constantly urinating is a good sign that your body is functioning well. Also, you need to think about how you need to burn fat physically, rather than only consuming black pepper. Some people believe that black pepper can be only consumed and it will help them lose weight. But you may be wrong if you only concentrate on consuming it rather than following some simple exercises such as walking and jogging. Always keep in mind that if you want to lose weight, the result lies in following a healthy diet and exercising at the same time. If you follow this, you will witness the results in a few mocking.

Currently, this spice has been added to almost all dishes because it brings in a sharp and spicy flavour to your dish. It is originally found in India and this spice was first valued when it was traded from Asia to Europe.