Our Superfood natural supplements that you can use in any food even as a spice or in any drink are also effective to restore your health or be used as a preventative to have a healthy and happy life full of positive energy.
The ingredients are exclusively from plants or mushrooms that have been dried and ground and mixed to obtain the specific effectiveness and are absolutely free of any chemicals. (Тhey are also great for your pets)
Our recommendation for a standard dose of consumption is half a teaspoon once or twice a day.
|Extract Solvent||Water & ethanol|
|Particle Size||98% through 80 mesh|
|Total Plate count||≤1000cfu/g|
|Yeast & mold||≤100cfu/g|
What is Apigenin?
Apigenin is a flavone, a specific subclass of flavonoids known to promote various health and longevity benefits. Chamomile tea, tabbouleh (Lebanese-style parsley salad), and celery juice are just a few examples of popular foods and beverages that are rich in this phytochemical. Like other flavonoids and flavones, apigenin functions as an anti-inflammatory and anti-cancer agent. What makes this compound unique, however, is its ability to reduce the incidence of age-related disease by promoting cellular apoptosis.
Most of what is known about apigenin has been gathered from cell and animal-based studies. Although apigenin-rich plants and teas have played a vital role in human culture for centuries, clinical trials are needed to better understand the efficacy, potential side effects, and ideal dosage of apigenin supplements.
However, apigenin consumption is widespread. Chamomile– a potent source of apigenin– is officially acknowledged as a medicinal drug in at least 26 countries, including Germany, Belgium, France, and the United Kingdom.
Product Description :
100g Pure Celery,Apigenin,Versulin,Smallage
Apigenin is also called apigenin and apigenin. It’s a flavonoid. It is widely distributed in nature. It mainly exists in daphneceae, Verbenaceae and Selaginellaceae, and is widely distributed in temperate tropical vegetables and fruits, especially in celery.
A large number of studies at home and abroad have found that apigenin has many biological activities, such as anti-tumor, cardiovascular and cerebrovascular protection, antiviral, antibacterial and so on
Apigenin can inhibit carcinogenic activity of carcinogens; As an antiviral drug for the treatment of HIV and other viral infections; MAP kinase inhibitor; Treatment of various inflammation; antioxidant; Calming and calming; step-down. Compared with other flavonoids (quercetin, kaempferol), it has the characteristics of low toxicity and no mutagenicity
How Does Apigenin Work?
Humans have enjoyed the medicinal value of plant compounds like apigenin for centuries. Modern research indicates these flavonoids have several mechanisms of action, exhibiting powerful antioxidant, anti-inflammatory, and anti-cancer effects. More specifically, apigenin research illustrates this compound’s unique therapeutic ability to promote apoptosis, prevent cancer, and reduce inflammation.
Treatment of Autoimmune Disease
Autoimmune diseases are characterized by the immune system attacking itself, typically as a result of being triggered by a foreign substance. It is estimated that more than 23 million Americans suffer with such conditions, which include things like rheumatoid arthritis and Celiac disease.
Modern medical research has increasingly looked toward polyphenols and flavonoids to help treat such disease, given the relatively low toxicity and tolerability of such compounds. In a systematic review of apigenin and four other popular flavonoids, researchers conclude such compounds exhibit “considerable potential” due to their antioxidant and anti-inflammatory properties.
This potential was put on display in 2014, when apigenin appeared to protect from the development of autoimmune myocarditis. Received apigenin treatments for just 21 days. Commenting on the study, researchers note apigenin significantly reduced cardiac hypertrophy and dysfunction, thereby alleviating the autoimmune response. Moreover, apigenin was found to calm the immune response by decreasing pro-inflammatory cytokines.
Reduced Risk of Cancer
A key characteristic of effective cancer treatments is the ability to selectively target and kill cancerous cells, without causing damage to healthy tissues. This is a difficult task, however. An estimated 65% of cancer patients lose their hair during chemotherapy, a stunning fact that demonstrates just how challenging it can be to selectively target cancerous cells with radiation therapy.
That’s why researchers are excited by the anti-cancer effects of phytochemicals like apigenin. Writing for the peer-reviewed journal Cell and Bioscience, researchers note that “apigenin shows significant cell cytotoxicity selectively against various types of cancer cells” while showing very little toxicity toward healthy ones. The keyword: Selectivity. Apigenin seems to naturally identify and shut-down cancerous cells while remaining minimally toxic toward surrounding tissues.
Interestingly, apigenin’s anti-inflammatory properties may help to explain its ability to function as an anti-cancer agent. Cancers often develop in areas plagued by irritation, which has led scientists to name chronic inflammation a “critical driver” of tumour progression. In this way, the anti-inflammatory properties of flavonoids like apigenin have the potential to prevent cancerous cell development and proliferation.
In one clinical trial, researchers studied the progression of colon cancer in 87 patients over the course of 3 to 4 years. Patients were divided into two groups. One took a daily flavonoid mixture consisting of 20mg apigenin and 20mg epigallocatechin-gallat (EGCG), an antioxidant catechin found in several varieties of tea. The other served as a control group, taking a placebo. Over 4 years, the group taking the flavonoid mixture experienced 0% cancer recurrence, while recurrence for the control group was an alarming 20%.
Prevention of Neurodegenerative Disease
Remarkably, certain flavonoids are known to promote cell development, proliferation, and network connectivity– often referred to as neural plasticity. There are likely many mechanisms of action, including the ability of flavonoids like apigenin to modulate the production of estrogen. Estrogen promotes neurogenesis (the creation of neurons) while also acting as a neuro-protectant. Increasingly, scientists are studying the efficacy of apigenin for promoting nervous system health and longevity.
Parkinson’s disease.To date, there is no cure for Parkinson’s. It is estimated this neurodegenerative disease affects more than 10 million people globally. Parkinson’s is the 14th leading cause of death in the United States, although the disease itself is not fatal. Increasingly, scientists are investigating flavonoids like apigenin to treat neurodegenerative conditions.
In a cell-based study, researchers in Brazil found apigenin to promote neuronal genesis and connectivity after binding to estrogen receptors in human stem cells. As a result, researchers believe apigenin may be able to promote neuron development, proliferation, and brain plasticity. Estrogens are also known to have neuro-protective effects. As such, researchers believe apigenin may also help to prevent the onset of neurodegenerative diseases.
Alzheimer’s disease. Dementia is the most common neurodegenerative disease, affecting a staggering 55 million people worldwide. Roughly 50-75% of patient cases are classified as Alzheimer’s disease, a specific kind of dementia characterized by loss of memory, speech, and decision making abilities. Like Parkinson’s, researchers hope to find unique flavonoids that can help to preserve nervous system function and delay the onset of such a devastating disease.
In a 2020 review of such research, scientists identify apigenin as a potential tool for delaying the onset of Alzheimer’s disease by acting as an antioxidant and cognition-enhancing compound. Scientists note apigenin appears to have “anti-amyloidogenic” properties, meaning it can prevent the formation of the amyloid plaque known to cause Alzheimer’s.
In a clinical review published one year prior, researchers came to a similar conclusion. After summarizing both animal and human trials, apigenin was identified as a potential therapeutic that may delay the onset of Alzheimer’s.
Reduced Feelings of Anxiety
Apigenin has been studied in both animal and human models. In both scenarios, the compound has been shown to decrease the symptoms of anxiety. However, it is important to note the experience of “anxiety” exists on a broad spectrum. On one end, symptoms are extremely mild and resemble that of excitement. On the other, symptoms are so extreme they cause shortness of breath, panic attacks, and even loss of consciousness. More research is needed to determine if apigenin can someday replace prescription medications for severe anxiety disorders.
In 2014, researchers demonstrated the anti-anxiety effects of apigenin in mice. The compound was extracted from Stachys tibetica Vatke, a tea native to the Himalayan mountains. This revered tea had been used by tribal healers for centuries to treat fever, cough, and even certain phobias. In the study, researchers found the apigenin extract to exhibit anti-anxiety effects, noting it could be an important molecule for future anxiety treatments.
Results have also been observed in human studies. In one double-blind, placebo-controlled trial, the compound was found to have a modest anti-anxiety effect on patients with mild to moderate Generalized Anxiety Disorder. For this study, participants received chamomile extract containing 1.2% apigenin.
Results were also seen in a long-term study of patients with Generalized Anxiety Disorder. Over 38 weeks, participants received either 1500mg of chamomile extract or a placebo. Results indicate long term chamomile use to be safe and significantly reduce symptoms of moderate to severe Generalized Anxiety Disorder.
It is important to note this study did not specify the exact concentration of apigenin in the chamomile extract. However, apigenin is known to be the primary compound behind the calming effects of chamomile. As researchers note, additional studies are needed to further understand the therapeutic potential of this tea.
What are the possible side effects of apigenin?
There is a very low risk of toxicity from apigenin and even when the side effects appear, they are likely to be mild. Some of the possible side effects of taking apigenin include: